4 Things to Secure in a Locking Box for Medicine (Plus 3 Not To)

Keeping potentially dangerous medications unsecured could have devastating consequences. Discover 4 that things need to be secured in a locking box for medications.

Accidental medicine poisoning or prescription drug misuse can be devastating to families. Among young children, 95% of medication-related poisoning visits to the ER were caused by the child ingesting medication while unsupervised. Safe medicine storage is critical to keeping your family safe.

Discover which medications should be locked away in a lockbox to help keep your loved ones safe.*

4 Things to Keep in a Medication Locking Box


Among people 12 and older, 9.3% misused opioids in the past year according to a survey by SAMHSA. And in 2021, opioid overdose deaths hit an all-time high, with one occurring in the United States every five minutes. The impacts of opioid misuse and addiction can be devastating. Help keep your household safe by safely securing any prescription opioids in a medication locking box.

Anti-Anxiety Medications

Some anti-anxiety medications like Benzodiazepines, also called Benzos, can come with a risk of dependency and withdrawal when used inappropriately. The rate of overdose deaths involving Benzos increased 8 times from 2002 to 2016. 75% of these deaths involved combined opioid use. If you have one of these medications in the house, it’s critical to make sure you’re using it as prescribed and storing it securely locked away in a medication lockbox.

Sleep Aids

Certain sleep aids like Ambien, Lunesta, Rozerem, and Sonata can have serious side effects including potentially life-threatening allergic reactions, hallucinations, etc. Medications like these can be less habit-forming than Benzos, but over time they can still sometimes cause physical dependence. Sleep aids can also be dangerous when mixed with alcohol, as the combination could cause someone to stop breathing. Keeping these medications locked away can help discourage inappropriate use.

Medicinal or Recreational Marijuana

In 2020, 17.9% of people 12 and older used marijuana, according to data from SAMHSA. Furthermore, 38 US states have legalized the medical use of marijuana by adults, and 19 of those have also legalized its recreational use.

Cannabis poisoning can be dangerous for children and pets, causing symptoms like difficulty breathing, walking, or sitting up. To help prevent poisoning, keeping any cannabis in your home secured in a lockbox is important.

What SHOULDN’T Be In Your Medication Lockbox

While medication should always be stored up and away out of the reach of children there are certain medications you may need to access quickly in an emergency. Because of this, you may not want to lock those up in your medication lockbox. This could include things like

  • EpiPens, which you may need quick access to in the event of a life-threatening allergic reaction.
  • Rescue inhalers for asthma attacks or other lung conditions.
  • Under-the-tongue nitroglycerin tablets for heart attacks.

These medications should be kept out of the reach of children, pets, and other household members but someplace immediately accessible in case of an emergency.

If you don’t yet have a plan in place for safe medication storage in your home, it’s time to create one for the health and safety of your loved ones and your own peace of mind.

*Keep in mind that this is a suggested starting point for your medication safety plan, not a complete list.


Baby at the beach wearing large sunglasses and a hat.
Baby Safety Travel Checklist

Whether it is the beach, a lake, a bustling metropolis, or just grandma’s house, baby safety never takes a holiday.

A worried mom holding her daughter looks at empty rx bottles. Find out how Safer Lock and Disposes Rx are protecting kids from medicine poisoning.
How to Protect Your Kids Against the Leading Cause of Poisoning at Home

Medicine poisoning and prescription drug misuse pose unique dangers to families with children. Find out how to protect your kids from the medicines in your home.

Image of over the counter cold medication gel caps removed from their packaging.
10 Warning Signs You Need a Medicine Box for OTC Meds

Did you know that securing your over the counter medications locked up and out of sight is is also an important part of medicine safety? Learn more.

Subscribe to our newsletter and get the latest news
and updates sent to you.